formula: analogue c20h28n4o2
molecular weight: 285.38
compound purity: > 99.7%
related substance: total impurities(%) ≤ 0.3%

IUPAC – methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate.

5F-MDMB-2201 is a synthetic cannabinoid (indazole family) very similar with MMB-2201. 5F-MDMB-2201 has very powerful action (agonism) at both the CB1 and CB2 receptors.
Systematic name: methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate
5F-MMB-2201 is a potent indole-3-carboxamide based synthetic cannabinoid, which has been sold as a designer drug and as an active ingredient in synthetic cannabis blends.

This synthetic cannabinoid receptor agonist (SCRA) is structurally related to MMB-2201 and has very powerful action (agonism) at both the CB1 and CB2 receptors.

It’s highly potent, showing activity in sub-milligram dosages, unsurprisingly for a fluorinated MDMB, or so I’ve read. Apparently this one becomes very intense and sometimes difficult and scary for cannabinoid-naive or even more experienced individuals, and at very low doses, perhaps even 1mg or less depending on bodyweight, metabolism, etc.

One user of another forum mentioned using 5F-MDMB-2201 at a dosage of 500μg and apparently experienced effects lasting up to the 8-hour mark, comparing it to, or in between, MMB-CHMINACA and FUB-AMB, but offered no more information beyond that.
Another, possibly more experienced user, on the same forum, reported using 5F-MDMB-2201 and reaching the ‘farthest depths of his mind’ with it, or something to that effect, in other words, having extremely introspective experiences with it.

Other than the above information, I’ve been unable to find and gather much else in the way of objective or subjective information. It sounds like this one may be promising for the cautious and dangerous for the impulsive or careless. Not enough seems to be known yet. This is not a cannabinoid that should be used by anyone who’s inexperienced with cannabinoids, inexperienced with dosing the crystalline form of chemicals with dosages nearly on par with LSD, or people without access to extremely accurate, reliable, and freshly calibrated precision milligram-scales.

This isn’t really the thread for all the rest of the cannabinoids and I created it specifically for 5F-MDMB-2201. In the interest of harm reduction I’d prefer to keep this thread more streamlined and clean, avoiding the buildup of information about other cannabinoids as that could lead to confusion and/or accidents with people who didn’t read the entire thread dosing a given chemical improperly. I plan to post the useful subjective information about 5F-MDMB-2201 if/when I can establish it to be true and I welcome everyone who has their own info about it to do the same, but it appears very few people have even tried this one yet.

In the interests of sharing information and safety, I will offer that you should always be assuming any synthetic cannabinoid making the rounds at this point (especially the ones you mentioned) to have a sub-milligram dosage range since so many of them do, and overdoses of these full-agonist synthetics can cause adverse and dangerous reactions such as seizure, heart attack, metabolic derangements and multi-organ failure at surprisingly low dosages not analogous to the partial-agonist/antagonist relatives found in nature.

0.2mg 5F-MDMB-2201 on 10g leaf? 0.2mg is one dose. If that ratio were correct you’d have to smoke all 10 grams almost instantly for it to be useful.

I can only assume you meant to write 200mg per 10g leaf, and that’s WAY too potent for almost anyone. At that ratio you’d have a product with 20mg 5F-MDMB-2201 per each gram of leaf. Nobody should follow the ratio outlined above. That’s a potentially lethally-strong blend depending on the density of the plant you’re using and the user’s bodyweight/tolerance/etc. You must warn people if you make comments like that! Lives are at stake, and if you don’t tell people how potent a ratio like that is, sooner or later you’ll likely end up causing the death of a person somewhere who’s too lazy to double check the math and the dosages for the chem. 5F-MDMB-2201 is active in the microgram/single-milligram range, and as far as I’ve read, an average dose of this chemical is between 200-500μg, or 0.2-0.5mg, for most users with a low to average tolerance level. A blend of 200mg/10g could easily have 10mg 5F-MDMB-2201 per bowl pack, or 20-50 individual “average” doses per each gram of the blend. One bowl of that could (and probably would) kill a person with no/low tolerance, or at least put them in the hospital if they’re lucky.

I really don’t mean to sound like a dick, but you absolutely must be precise when other people’s lives are the possible cost of any numerical or mathematical mistakes you might make. This is very irresponsible.

I might go with 2mg per 10g grams of leaf (20mg per 100g of leaf,) personally. That’d be 0.2mg 5F-MDMB-2201 per each gram of leaf. That’d be a much more reasonable and relatively “safe” ratio that’d allow someone to smoke a bowl or two, I think, from what I understand of the extensive reading I’ve done.

5f mdmb 2201 sucess story
1g. Maybe up to 1.2 g. 2oz acetone. Shake 5f in acetone until its clear with yellow tint. In a quart mason jar put in 1oz to 32g herb. I used 1oz pf some fluffy catnip from freaking wally world for $3. I poured the acetone noid mix into the jar of herb. Quickly sealed on cap and shook like hell. Turning it upside down and shaking alternating from right side up. Hell, even side to side. After a minite or 2 shaking in this manner i opened thejar and stirred the herb soaked acetone to make sure no dry spots. I shok it all again for a couple more minutes. Poured it all out on a sheet of foil amd let it air dry. Mixed it up by hand a little bit and its fire. My plants love it. One of their favs second to amb fub
As long as you make it like 1:100-120 and start really really small just to be safe, you should be fine. I’ve heard not to make it anymore potent then 10mg to a g on another forum but hardheads might very well make it stronger, this is all passed on knowledge, I have yet to try any of these next gen noids yet.

5f-mdmb 2201 is way strong be careful.
Pink tint stinks to high heavens extremely potent even in micro doses makes fab 144 look like a little baby

Been using 5f-mdmb-2201 for a few weeks now at varying doses. I got a nice dose for e liquid right now.noid makes me nod out alot, and makes me really sleepy if I’m laying down. Gives me the munchies alot and the aftereffects last about 8 hours. Overall very please ny noid and lasts a long time.

Just wanted to throw in my two cents, as someone who has practically zero experience in synthetic noids. I have lots of experience with all kinds of RCs but always just stuck to weed over messing with anything synthetic. At first I was extremely cautious considering the low dosage but one day after a couple beers I decided fuck it, rubbed a negligible amount of mdmb-2201 on a paper clip, got a straw, burned it off and inhaled the tiny bit of smoke that came off of it. About 5 – 10 minutes pass and I immediately noticed paranoia (this is common for me and weed as well) then I let it sink in, and was really just blown away. I felt like I just smoked half a joint. I was and still am amazed, partially, I think, cause this is the first RC I’ve experienced that I could smoke. Tried it again the next night and had an even better experience. It’s so clearly hitting cdb receptors and frankly I might be in love. I’m still about to get my medical card, essentially making this chem useless to own for me, but wow. I’m glad I found this and tried it.

Edit: so after a couple more experiences, I’ve determined that the effect lasts a couple hours, similar to thc. I read on another post dangers of these substances being addictive, I dunno if I see it, but am not gonna comment after only a few days of use. I’ve experimented with different amounts, and so far haven’t overdone it. I can’t speak for anyone else but it seems safe enough for me. I also live a somewhat reckless lifestyle.

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