RAD140

Name: RAD140
CAS No: 1182367-47-0
Molecular Formular: C15 H23 Cl N2 O
Appearance: White fine powder
Quality:98% by HPLC
Function:New generation supplements for gaining mass and cutting edges
Assay:HPLC;HNRM;LC-MS

RAD 140, also known as Testolone, is an orally bioavailable, non-steroidal, selective androgen receptor modulator that has the ability to increase lean muscle mass and reinforce the effects of testosterone without the unwanted side effects of anabolic steroids.


What is RAD-140?
RAD140, from its internal nonsteroidal selective
androgen receptor modulator (“SARM”) discovery program, for full preclinical development as a
potential therapy for the treatment of age-related muscle loss (sarcopenia) and other
musculoskeletal conditions such as osteoporosis. Radius selected RAD140 from a series of
promising SARMs after it demonstrated exceptional selectivity for anabolic activity in well-
validated in vivo models. Radius expects to complete formal toxicology studies that will allow
This makes its usage significantly safer and more effective compared to traditional prohormones and anabolic steroids.

According to the Cambridgebased pharmaceuticals company Radius, the potent, orally bioavailable and nonsteroidal RAD 140 SARM is designed to make the hormonal receptors in the tissues of the body act the same way as if they’re getting a good dose of testos, setting off the same effects as if you’re cycling with prohormones and anabolic steroids minus unwanted side effects.
Moreover, clinical studies also show that RAD 140 SARM also has a few other benefits, which we will discuss more thoroughly in a moment.

Benefits when you use RAD 140 SARM:

Enhanced speed, stamina and endurance during high-intensity workouts
Faster buildup of muscular tissues that helps you achieve more gains in a shorter period of time
Based on medical tests, Rad140 SARM also displayed a greater anabolic effect than testoste when used. 

  1. RAD140 helps increase muscle mass
    The number one benefit of supplementing with RAD140 is its ability to increase lean tissue without increasing fat. In fact, during initial studies done on monkeys, scientists observed an average weight gain of more than 10% in just 28 days. This was done using only RAD 140 and without any adverse side effects traditionally related to testosterone.
  2. RAD140 may enhance speed, stamina, and endurance during high-intensity workouts
    Want to work out longer, harder and get better results every time you hit the gym? Reports of enhanced speed, stamina, and endurance during workouts are common when supplementing with Testolone. Additionally, thanks to its ability to increase lean muscle tissue and decrease fat, high-intensity workouts and interval training can be optimized every time.
  3. RAD140 has a greater anabolic effect than testosterone
    Similar to other SARMs such as LGD4033 (Ligandrol) or S4 (Andarine), RAD140 produces similar results to testosterone but without the side effects.

RAD140 interacts with the hormonal receptors of muscle and bone tissue in the same ways as larger doses of testosterone, all without the estrogenic side effects caused by anabolic steroids.

Many users on forums also report greater anabolic effects than testosterone and are sometimes used as a PCT for steroid users to retain muscle mass between cycles.

  1. RAD140 may reduce the side effects of testosterone
    When taken in conjunction with anabolic steroids, initial studies indicated that RAD140 reduces the side effects of testosterone stimulation on the prostate and seminal vesicles of monkeys .

Additionally, many anabolic steroid users report concerns for the health of their liver. However, during the 28-day trial, these monkeys also showed minimal liver enzyme elevations on a dose 10x higher than the fully effective dose, even though a weight was gained during a short timeframe (which can cause liver strain).

Our advice?

With the results from RAD140 already proving better than anabolic steroid use, users may be better off forgetting testosterone altogether and sticking to SARMs.

  1. Testolone does not appear to have the same side effects of anabolic steroids on reproductive organs
    Initial studies on mice have found that low doses of RAD140 are all that’s needed to stimulate muscle growth without affecting the weight of the prostate.

This means that RAD140 has the ability to selectively stimulate muscle and bone growth while reducing the effects on sex tissue such as the prostate or clitoris. (So yes, this means RAD140 is safe for women)

  1. RAD140 may aid weight loss by increasing fat loss
    RAD140 indirectly reduces body fat by increasing muscle and bone cells, which are more metabolically expensive to maintain than fat cells. By increasing muscle mass, an increase in the metabolism is seen, which results in easier weight loss .

Users also report increased muscle growth and decreased fat stores thanks to RAD140’s ability to increase stamina, endurance, and speed during an interval training.

  1. RAD140 is being trialed for the treatment of breast cancer
    RAD140 was discovered and is currently being developed by pharmaceutical company Radius specifically for the treatment of Androgen Receptor (AR) and Estrogen Receptor Positive (ER+) breast cancer in postmenopausal women.

In vitro studies completed in 2017 showed that RAD140 inhibited the growth of AR/ER+ breast cancer cells. Results from these studies supported further investigation of RAD140 as a breast cancer treatment, and the first human clinical trials were brought forward .

  1. RAD140 is indicated to be neuroprotective for brain health in neurodegenerative diseases
    As testosterone levels in men decline, the risk of disease in androgen-responsive tissue (including the brain) increases, implicating the development of neurodegenerative diseases such as Alzheimer’s Disease.

However, treating AR diseases with testosterone may increase the risk of prostate cancer. Recent studies suggest that RAD140 may be as effective as testosterone in reducing cell death without side effects to the prostate.

RAD140 Side Effects
As with most SARMs, studies show that RAD140 does not appear to have any side effects common to steroidal compounds. Unlike testosterone, RAD140 does not cause prostate enlargement or testicular shrinkage.

However, as it is still in early developmental stages, this does not mean that there are no long-term effects. Some user-reported side effects include headaches or insomnia that disappear with correct dosage.

Researchers pointed out that besides having a more “reinforced” effect than testoste, RAD 140 SARM was also seen to help reduce the androgenic side effects that can be potentially caused by the same on the prostate.

How RAD140 Works
The androgen receptor (AR) primarily targets normal human sexual development, but its activation by compounds (such as testosterone) also affects bone, muscle, liver and the central nervous system.

The problem within the medical and bodybuilding communities is that using testosterone to activate AR signaling for increased muscle and bone development also affects the sex tissues, resulting in testicular atrophy, enlarged clitoris in females and even risks of prostate cancer.

RAD140, a nonsteroidal selective androgen receptor modulator (SARM) bypasses this issue. Due to the way RAD140 binds to the androgen receptor, different cells respond by releasing different proteins, with only some androgen receptors being activated throughout the body.

This stimulation results in androgen receptor activation in bone and muscle cell, rather than raising liver enzymes or affecting sexual tissue.